Los Angeles to Phoenix is one of the busiest freight corridors in the Southwest, running along I-10 through the desert. Here is what to expect if you are moving a shipment on this lane. Distance and transit time The route runs roughly 370 to 390 miles depending on the exact origin and destination, mostly along I-10. A dry van or reefer running solo can typically cover this in a single day, including a stop, which makes it a common same-day or next-day delivery lane. Typical e